ASSESSMENT OF THE CONCRETE STRENGTH USED IN STRUCTURES, USING THE DESTRUCTIVE METHOD


Visual evoked potentials waveform analysis to measure intracortical damage in a preclinical model of multiple sclerosis

IntroductionVisual evoked potentials (VEPs) are a non-invasive technique routinely used in clinical and preclinical practice.Discussion about inclusion of VEPs in McDonald criteria, used for Multiple Sclerosis (MS) diagnosis, increased the importance of VEP in MS preclinical models.While the interpretation of the N1 peak is recognized, less is know

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The UBA-UIM domains of the USP25 regulate the enzyme ubiquitination state and modulate substrate recognition.

USP25m is the muscle isoform of the deubiquitinating (DUB) enzyme USP25.Similarly to most DUBs, data on USP25 regulation and substrate recognition is scarce.In silico analysis predicted three ubiquitin binding domains (UBDs) at the N-terminus: one ubiquitin-associated domain (UBA) and two ubiquitin-interacting motifs (UIMs), whereas no clear struct

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